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Toxicol Pathol 25, 25663

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Ito, T., Yagi, S

BDNF is one of the brains primary endogenous growth factors, making this a significant benchmark for Dihexas neurological activity

Although the predicted template modeling (pTM) score (~0.5) indicates moderate confidence, the computational results are consistent with the -helical propensity observed by CD analysis (Fig 4B)

The researchers noted these drugs (along with Mounjaro and Zepbound) are glucagon-like peptide receptor agonists (GLP-1s), which work to suppress appetite by targeting specific receptors in the brain