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It was first described in research as an exercise-mimetic a compound that activates some of the same cellular pathways triggered by physical activity, even in sedentary states

Activation of the Hippo/TAZ pathway is required for menstrual stem cells to suppress myofibroblast and inhibit transforming growth factor signaling in human endometrial stromal cells

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Nevertheless, translating these findings to human populations requires caution, as metabolic responses can differ substantially between species