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Jean-Pierre Raufman, M.D., Baltimore VA Medical Center (formerly with State University of New York Health Science Center) Selected publications: Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom

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Compared with THC, which expresses its effects through the weak partial agonist activity of CB1 and CB2 endocannabinoid receptors, THCV acts as a neutral CB1 antagonist and partial CB2 agonist

Wound Healing: Demonstrated acceleration of wound closure through angiogenesis stimulation, fibroblast proliferation, and metalloproteinase modulation

Conversely, ferroptosis can feed back into the gut via metabolic products such as ROS through blood to aggravate gut dysbiosis, and then form a self-enhancing ferroptosis-gut dysfunction cycle in OA

Petrus P, Lecoutre S, Dollet L, Wiel C, Sulen A, Gao H, et al