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Pre-treatment preparation includes: Thorough cleansing with an antibacterial cleanser Avoidance of makeup, retinoids or exfoliants 48 hours before the procedure Avoiding active breakouts or infections Post-treatment skincare routines and product recommendations Proper post-treatment care supports healing and minimises the risk of breakouts

All of the solutions were freshly prepared immediately before synthesis as stock solutions in DMF: Fmoc-protected amino acid (0.2 M), HCTU (0.5 M), DIPEA (1.0 M) and piperidine (20% v/v)

Until now, it hadnt been tested for weight-loss maintenance in a longer-term randomized clinical trial