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However, platinum-induced peripheral neuropathy (PIPN) caused by the accumulation of Pt in the peripheral nervous system limits the clinical application, whose prevention and treatment are still a huge challenge

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Pycnogenol supplementation with 200 mg a day for eight weeks significantly lowered blood systolic blood pressure from 140 to 133 mmHg compared to placebo, which was decreased only marginally

DSIP is a neuropeptide originally isolated from thalamic tissue, administered exogenously in research, and studied for sleep architecture modulation

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