After filtering to retain participants with information regarding pre-treatment and post-treatment BMI and genotype data passing quality control, we obtained 4,889 participants, of which 3,948 had complete data when incorporating covariates akin to those used in the GWAS
Careful design and modification of NADs can mitigate immunogenicity, but this requires extensive testing
Treat the underlying cause completely and consistently antivirals, immune-modulating therapy, metabolic management, or alcohol cessation
[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Sjostrom L, Peltonen M, Jacobson P, Ahlin S, Andersson-Assarsson J, Anveden A, et al
This could be of special importance for long neural genes, for which regulation might need several layers of monitoring to safeguard transcript quality
doi: 10.2460/ajvr.67.7.1173