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doi: 10.1073/pnas.131200398 31 SamolsEMarriGMarksV

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It is a unimolecular formulation based on the GIP structure, with structural modifications to the peptide chain that enable interaction with both GLP-1 and GIP receptors.39 Its biological action on the GIP receptor is five times greater than that on the GLP-1 receptor.39 Effects on weight loss, body composition and diabetes prevention The SURMOUNT programme shows that TZP reduces weight in a dose-dependent manner, achieving a 22.5% weight reduction at the maximum weekly dose of 15 mg40 (Table 1)

Asimismo, la cantidad de peso perdida con la retatrutida iguala o supera la que se pierde tras someterse a una ciruga baritrica

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