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These centered estimates were plotted against their standard errors, and visual symmetry was assessed using overlaid confidence contours at the 90%, 95%, and 99% levels

K., Karadas, B., & Kaplan, Y

What if semaglutide isn't working fast enough for me

This article from 2015 does a good job conveying the boom-bust cycle around miracle weight loss drugs pre GLP-1s, and the resulting skepticism with which the medical establishment viewed the category

The test identifies your genetic predispositions across 14 metabolic pathways, revealing whether you'll likely respond well to semaglutide or whether alternative GLP compounds might work better

V., Lowy, D