His curiosity aroused, over the subsequent decades, he and other scientists identified many different effects the hormone has on the body, and how the hormone could be turned into a drug
Inhibition of these cytokines also reduces surface expression of cellular adhesion molecules, reducing migration of activated lymphocytes into synovial tissue in PsA, and limiting the bone and cartilage damage by proteases released by these inflammatory cells
Wensink, D., Wagenmakers, M
Wen W, Li H, Lauffer M, Hu D, Zhang Z, Lin H, Wang Y, Leidinger M, Luo J
Body Composition and Lean Mass Preservation Research demonstrates tesofensine produces favorable changes in body composition, with weight loss derived primarily from fat mass reduction while preserving lean muscle tissue
PMID: 38733771 SSRN2023 Nov 17