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Based on in vitro studies, CYP3A4 and CYP2D6 enzymes are responsible for dehydrogenation and hydroxylation of aripiprazole, and N-dealkylation is catalyzed by CYP3A4

Indication: Thick or treatment-resistant warts, especially in older adolescents or adults

Because of gastric transit time

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This balance supports beneficial vasodilation without the tissue damage associated with excessive nitric oxide production during inflammatory states

The animal data offers a partial explanation