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Induction of apoptosis was detected by Propidium Iodide (PI, 1 g/mL) (Sigma Aldrich) and Annexin-V-APC (Immunotools) staining, followed by flow cytometry analysis, using a BD FACSCantoII flow cytometer

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The FDA approved it for patients who have uveal melanoma, a rare melanoma that develops in the tissues of the eye, when surgery is not an option or when the cancer spreads (metastasizes)

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