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Using macrophages, Lin et al

Vrieze A, Van Nood E, Holleman F, Salojarvi J, Kootte RS, Bartelsman JF, et al

Although a single dedicated receptor has not been conclusively identified, experimental research indicates that BPC-157 influences several interconnected molecular systems, particularly nitric oxide signaling, angiogenic regulation, and focal adhesion associated pathways [1]

This upregulation leads to an increased expression of lipogenic genes, including sterol regulatory element-binding proteins (SREBP1c) and diacylglycerol acyltransferase-2 (DGAT2), which suggests that miR-370 provides a further point of regulation of this pathway 86

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