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DSM criteria describe a persistent, recurrent pattern marked by tolerance (needing increasing amounts of money), irritability when trying to stop, chasing losses, and significant life impairment, features clinicians use to diagnose the condition
31 Over time, a third phase of stabilization, erosion and ulceration of the colonic mucosal epithelium may be accompanied by bleeding and the secretion of large amounts of mucus, with relatively stable symptoms that require long-term treatment and management to prevent recurrence
