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Unlike mRNAs, which are rapidly degraded, circulating miRNAs are protected from endogenous RNase activity by being encapsulated within extracellular vesicles (EVs), such as exosomes, or by forming complexes with proteins like Argonaute2 [18]

doi: 10.3389/fimmu.2022.944683 70 LiYLiuHYeSZhangBLiXYuanJet al

Moreover, the same recovering effect on the disabled muscle function occurred with a much later therapy application

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[9] [10] For patients with type 2 diabetes, who already face increased risk of diabetic neuropathy, maintaining optimal B12 levels is particularly important to avoid compounding neurological complications