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In addition, altered expression of genes that regulate serotonin signaling and function in the ovaries of the offspring of fluoxetine-treated animals may occur in combination with the increased expression of components of the regulatory loop of the core circadian locomotor output cycle Kaput ( Clock ) gene, suggesting interactions between serotonin and Clock gene signaling pathways can lead to an altered reproductive phenotype

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demonstrated that GLP-1 activates the cAMP/PKA signaling pathway by binding to its receptor GLP-1R and by then phosphorylating the PKA consensus site of NHE3 (101)

Mahboob A, et al