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GLP-1s for Chronic Kidney Disease GLP-1s for Advanced Liver Disease In August 2025, the FDA approved Wegovy (semaglutide) to treat adults with a type of liver disease called metabolic-associated steatohepatitis (MASH) with moderate to advanced liver scarring (fibrosis), when used alongside diet and exercise

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Of these, around 150,000 were treated with GLP-1 drugs, and around 1.5 million were treated with insulin

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Lancet (2023)