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Systemic consequences of pulmonary hypertension and right-sided heart failure

And its similar to the cancer risk from obesity or a sedentary lifestyle

A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: a scientific statement from the American Heart Association

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GLP-1 exerts anti-inflammatory effects by suppressing the NF-B signaling pathway, which leads to a decrease in the production of pro-inflammatory cytokines like TNF- and IL-6, thereby mitigating liver inflammation and fibrosis

Biochem Soc Trans 39(4):11021106