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Dehydration is a common and overlooked cause of tiredness

Among them, GLP-1 and GIP (gastric inhibitory polypeptide) are known as incretins, gut-derived hormones that enhance glucose-dependent insulin secretion, playing a pivotal role in maintaining glucose homeostasis and serve as important therapeutic targets for type 2 diabetes and obesity

Experimental data indicate GLP1-S enhances peripheral glucose uptake, lowers hepatic glucose output, and slows gastric emptying

Key findings from the Phase 2 data included: Dose-dependent weight loss : Greater reductions in body weight were observed with higher doses, suggesting a clear pharmacological dose-response relationship

Emptage I et al

Retrieved from Lewis, K