It declines with age, and lower NAD+ is associated with slower metabolism and the changes we lump together as getting older. NNMT, meanwhile, consumes the raw materials your body uses to make NAD+ and in fat tissue, NNMT is often overexpressed, which can drag NAD+ down right where you least want a sluggish metabolism
[PubMed Citation] 19
The DNA damaging revolution: PARP inhibitors and beyond
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MOTS-c has also garnered attention for possible benefits related to aging
