To determine the solution structural model of the p53 TAD2 -FOXO4-DRI complex using NMR spectroscopy, we recorded several sets of NMR experiments on two types of complexes: 13 C, 15 N-labelled p53 TAD2 -FOXO4-DRI and 13 C, 15 N-labelled FOXO4-LRI D -p53 TAD2 (see methods)
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Studies indicate that GHK-Cu may stimulate the production of collagen types I, III, and V, as well as elastin, decorin, and glycosaminoglycans in fibroblast cell cultures
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This work was supported by the National Natural Science Foundation of China (32371255 and 32071203 to LHZ, 32130022 and 82121005 to HEX, 82404881 to QNY)