These studies demonstrated a decreased dendritic spine number in the cortex [373] and hippocampus [374]
doi: 10.3390/ijms21176336 133 LanfrancoM
"These guidelines will help all providers who care for patients treated with immune checkpoint inhibitors, not just oncologists, but also emergency room and primary care doctors, assess and manage these side effects." Key guideline recommendations: In general, checkpoint inhibitors can be continued with close monitoring for mild (grade 1) toxicities, with the exception of neurologic and some hematologic toxicities
Transient hypothyroidism or persistent hyperthyrotropinemia in neonates born to mothers with excessive iodine intake
Currently, there is no cure, though some medications slow progression in select patients
Children with hereditary mevalonate kinase deficiency frequently exhibit febrile or afebrile seizures, underscoring the in vivo relevance of this metabolic pathway (34)