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Cross-Trial Context# Retatrutide's 24.2% weight loss at 48 weeks appears numerically superior to semaglutide's 14.9% at 68 weeks, but several factors complicate direct comparison: Trial phase : Phase 2 trials often yield more favorable results than Phase 3 (smaller, more controlled populations) Treatment duration : Semaglutide data are at 68-104 weeks

8 mg weekly stands as a proven alternative [2]

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While there is no clinical data specifically supporting this practice for injection sites, general dermatological principles suggest that well-moisturized skin recovers faster from minor trauma

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