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FOXO4-DRI has three main pharmacogenetic advantages: its stability (resistance to degradation by cellular proteases), half-life (compared to L-peptide equivalents, it's longer), and cell-penetrating properties (cell-penetrating sequences improve intracellular delivery)
"We have seen our a1c's lowered drastically patients have gotten healthier so I think it's a great thing." GLP-1S cover a wide range of medication
however, the specific mechanism of action needs to be studied in depth (166)
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Normally, when you eat, the lower esophageal sphincter (LES)a muscle that acts as a valve between the esophagus and the stomachopens to let food in and then closes tightly to keep acid out