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Ingrained in my DNA

In other words, too much of a signal will result in a resistance to the signal, which is a fundamental principle of biology, whether its cancer, biology, and chemotherapeutics, whether its antibiotics to treat infections, and even hormones

Heard K, Rumack BH, Green JL, et al

In this Review, we evaluate the translational evidence supporting GLP-1RAs as candidate disease-modifying therapies for NDDs, describe mechanistic pathways linking metabolic dysfunction to neuronal vulnerability, and outline remaining challenges and research priorities in this rapidly evolving field

SIDE EFFECTS: Testicular shrinkage

Oral bioavailability of peptides is notoriously low due to enzymatic degradation in the GI tract