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GLP-1R agonists Several GLP-1R agonists, which mainly delay protease DPP-4 metabolism to overcome the problem with the rapid inactivation of GLP-1, have been developed (5, 119)

Semaglutide may modestly reduce triglycerides, but severe hypertriglyceridemia should be addressed before initiation

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Bioregulator peptides like Pinealon tend to be among the most affordable options, with small tripeptides costing less to synthesize than larger, more complex molecules

Ultimately though, the antifibrotic effects conferred by compounds derived from TCM target critical signaling nodes such as TGF-/Smad which play pivotal roles in EMT and ECM synthesis (Na et al., 2018) (Figures 2, 3)