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Ascaris suum -derived products induce human neutrophil activation via a G protein-coupled receptor that interacts with the interleukin-8 receptor pathway

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Overexpression of ChaC1 in yeast caused significant GSH depletion and increased apoptosis, which could be reversed by adding glutathione, linking ChaC1s role in GSH degradation to apoptosis (Kumar et al., 2012)