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Reduced MTHFR activity reduced methionine regeneration reduced SAM production reduced methylation capacity across all SAM-dependent methyltransferase reactions consequences that propagate through epigenetics, neurotransmitter metabolism, creatine synthesis, phosphatidylcholine production, and the broader biochemistry that SAM sustains

However, the specific role and mechanism of ferroptosis in endometriosis, as well as in endometriotic infertility, remain unclear

Regardless of these limitations, the results of this review provide valuable insights regarding ivermectin mechanisms that have been identified in relevant ectoparasites in previous research and may inform future research and resistance monitoring strategies

The regulation of diverse transcription factors, receptors for growth factors (including FGFR2b, FGFR2c, EGFR and HER2), and the activation of Akt are other elements in the reversion of MET [24]