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After analyzing NorstellaLinQ EMR and open claims data, we found that approximately three-quarters of patients initiating oral Wegovy had not previously received a GLP-1 injection

R.LiL.YangY.-X.CaoY.YuX.et al (2024)

GLP-1 Therapy GLP-1 Semaglutide and tirzepatide are in a class of medication called GLP-1 (glucagon-like peptide) that have been used for diabetes treatment for many years

Considering the increasing use of GLP-1 RAs in obesity and among patients on psychotropic drugs, further research is essential to evaluate psychiatric safety in high-risk populations

So this is a hugely contemporary topic in both the US and the UK as far as a weight loss drug

But theyre also a reminder of what sustained investment in basic science can achieve. As UAB researchers continue to study how these drugs work and what comes next, their findings are helping move the conversation beyond hype, while working toward a clearer understanding of one of the most significant medical breakthroughs of the past decade.