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Importantly, gastrointestinal adverse events (nausea, vomiting, diarrhoea) occurred in 3045% of participants during dose escalation but typically resolved within 48 weeks

Eli Lilly is expecting results from several more phase 3 trials of retatrutide for obesity and type 2 diabetes this year, a spokesperson told Scientific American

Therefore, minimizing your exposure to toxins is vital if you have one or more MTHFR gene mutations

Concurrent use is not recommended as the safety and efficacy of such combinations have not been established

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The main concerns are quality control and lack of long-term human data