However, these ads are misleading
Women with PCOS, especially those who had irregular periods before starting GLP-1s, may take longer to establish regular cycles
Receptors GLP-1 GLP-1 + GIP GLP-1 + GIP + Glucagon Class Single-agonist Dual-agonist Triple-agonist Generation First Second Third Brand Names Ozempic / Wegovy Mounjaro / Zepbound Not yet approved Phase 2 Weight Loss (peak) ~14.9% ~20.9% 24.2% Approval Status FDA approved FDA approved Phase 3 trials A common question: is the difference between 20.9% (tirzepatide) and 24.2% (retatrutide) really that significant
PMOS also tends to be associated with excess weight, although people at a healthy weight can also have the condition, says Marilyn Tan, MD, an endocrinologist at Stanford Medicine in California
Moreover, for adults with type 2 diabetes or prediabetes and nonalcoholic fatty liver disease (NAFLD), the ADA suggests considering GLP-1 receptor agonists or dual GIP/GLP-1 receptor agonists as part of the treatment plan
[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Gerich JE