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Its mechanism of action is based on selective activation of the ghrelin receptor (GHS-R1a), which signals the hypothalamus and anterior pituitary to increase pulsatile GH secretion

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The clinical research currently consists of the following: Small 1980s pilot trials No large modern RCTs Limited pharmacokinetic clarity No validated subcutaneous dosing protocol for improved sleep DSIP likely works for many individuals, but its critical to acknowledge the doses used by the biohacking community comes from extrapolation

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