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Semaglutide GLP-1 pathway Semaglutide is a GLP-1 receptor agonist already FDA-approved for chronic weight management as Wegovy (2.4 mg) and for type 2 diabetes as Ozempic

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Step therapy can be waived with documented contraindications or prior intolerance

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Retatrutide: A Substance in Clinical Trials Retatrutide stands out as it is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors, showing promise in clinical trials for obesity and type 2 diabetes management