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The contemporary research framing places the compound in a research-supply position rather than a clinical-development position

[53] Four additional trials (NCT03131687, NCT03311724, NCT03861052, and NCT03861039) were included in the safety evaluation, for a total of 7,769 adult participants with type 2 diabetes

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However, given that the healthy gut is immunologically primed to detect and prevent bacterial penetration, it is likely that an integral homeostatic signaling mechanism, which maintains the integrity of the gut barrier, exists to facilitate microbiota-gut-brain signaling