Specific genetic variants in GLP1R, GIPR, FTO, and MC4R genes influence receptor sensitivity, appetite regulation, and baseline metabolic rate, affecting both efficacy and tolerability
Given the importance of adequate nutrition before, during, and after GLP-1 use, clinicians and individuals must be equipped with knowledge and skills around healthy eating
GLP-1s help reduce blood sugar fluctuations, which might prevent nighttime awakenings caused by hypoglycemia or hyperglycemia in people with type 2 diabetes
So we highly recommend using it only once a day
Circadian clocks and metabolism
This can provide additional benefits for muscle growth and energy