Verdict: Better than nothing, but youre hoping your body does the work
J., Friedrich, M
Notwithstanding about the promising mechanisms of action, translation to patients is limited by bioavailability and pharmacokinetic issues, inter-subject variability and possible interactions with other chemotherapeutic agents or endocrine therapies highlighting the need for well-conducted randomised controlled trials and PKPD studies (248)
This powerful molecule is also involved in the metabolism of toxins, helping to convert them into water-soluble compounds that can be easily excreted from the body
Dan W, Yiling J, Chun L, Jing F, Huimin W, Xiaoxin Y (2021) Withaferin A downregulates COX-2/NF-B signaling and modulates MMP-2/9 in experimental endometriosis
"Catalytic cycle of human glutathione reductase near 1 A resolution"