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Theocharidis, G

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DNA concentration was determined with a Qubit dsDNA BR Assay Kit (Thermo Fisher Scientific) and Qubit fluorometer (Thermo Fisher Scientific)

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The latter binds to RAGE, leading to an increase in NF-B-dependent pro-inflammatory gene expression, suggesting that CML-S100A8/S100A9 generated in inflammatory lesions can elicit a RAGE-dependent inflammatory response (129)