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This observation suggests that the displacement of L1 by the weak binding of a second IGF1 may disrupt the functionally important L1FnIII-2 interaction, which may lead to suboptimal receptor activation

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270,271 Additionally, slower gastric emptying helps stabilize postprandial blood glucose levels

Limitations Although LGE is useful for reproducible assessment of myocardial scarring and replacement fibrosis, it is limited in its accuracy in the assessment of diffuse fibrosis