Several studies have reported increased oxidative damage as evident by increased lipid peroxidation, protein and DNA oxidation as well as decreased antioxidant status (enzymatic and non-enzymatic) indicated by glutathioneredox imbalance and decreased activities of antioxidant enzymes in the blood, urine and brain tissues of subjects with autism
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Antioxidants (Basel) 12 (10), 1867
To explore the underlying mechanisms, the proteomics change in APP-treated serum was investigated through LCMS/MS and bioinformatics analyses