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Smoking cessation, if applicable, represents perhaps the single most impactful additional cardiovascular intervention

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2018 Sep;32(9):5051-5062

L-carnitine supplementation mitigated these mitochondrial alterations, restored mtDNA levels, and enhanced -oxidation capacity (43, 72, 73)

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Functional outcomes such as changes in mobility as measured by gait speed over 10 meters [also see (262)], as well as measures of cognitive impairment