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Body measurements show waist decreasing while arm and leg circumference holds steady or even increases slightly as body fat percentage drops

refer to the NHS medicines information pages and the MHRA/EMC SmPC for eligibility and safety details [13] Semaglutide (Wegovy) approved by the MHRA and recommended by NICE (Technology Appraisal TA875) for weight management in eligible adults (BMI 35 kg/m with at least one weight-related comorbidity, or BMI 3034

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In the over 2500 participants, who were assigned to the 5, 10, and 15 mg doses of tirzepatide and placebo, the percent weight changes were both statistically and clinically significant compared with placebo

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