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Courts apply the discovery rule differently across jurisdictions, with some requiring actual knowledge of the medication link while others impose constructive knowledge based on when a reasonable person would have investigated the connection

Dosing usually starts low (e.g., 0.25 mg) and gradually increases over several weeks (up to 2.4 mg for weight loss or 2.0 mg for diabetes), depending on your tolerance and goals

The foods most likely to be well-tolerated when nausea is present tend to be low in fat, mild in flavor, and moderate in volume

Although deletion of CARS2 in mice is embryonic lethal, mice with a heterozygous knockout of CARS2 showed approximately 50% lower levels of supersulfides compared with wild-type mice, indicating a predominant role of mitochondrial CARS2 in supersulfide production (15) ( Figure 2 )

(2025) 12:e2413759

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