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Prenatal exposure to GLP-1 receptor agonists and other second-line antidiabetics may not pose greater risk to infants than insulin For immediate release: December 11, 2023 Boston, MAInfants born to women with pre-gestational type 2 diabetes who take second-line non-insulin antidiabetic medications (ADMs) during pregnancy are at no higher risk of major congenital malformations (MCMs) than infants born to those who take insulin, according to a new study led by Harvard T.H

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The researchers concluded that AOD-9604 represents a promising fat-reducing alternative to growth hormone therapy without its associated metabolic risks, particularly regarding glucose regulation and IGF-1 elevation

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While SUSTAIN-6 and REWIND trials examined GLP-1 RA in diabetics with different cardiovascular risk profile, The Harmony Outcomes study enrolled patients with T2D and established atherosclerotic cardiovascular disease (ASCVD)