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In contrast, we found that these metabolomic alterations led to a reduction in the plasma level of 66 different metabolites in acute patients versus the R group ( Supplementary Figures 9A-C )

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10.1016/j.lungcan.2012.05.107 Lung Cancer Summary Keywords GSTP1, cancer, epigenetics, DNA methylation, histone modifications, epimutations, biomarker Citation Schnekenburger M, Karius T and Diederich M (2014) Regulation of epigenetic traits of the glutathione S -transferase P1 gene: from detoxification toward cancer prevention and diagnosis