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ERK1/2 phosphorylation and AKT expression elevated in preclinical models

Stable for years under reasonable conditions

The compound's half-life and bioavailability also differ significantly from peptides

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In such a task, network models are useful tools as they methodically address complex disorders by looking at dysregulated modules rather than the effects of individual mutations or genes in the conventional reductionist paradigm (Williams and Auwerx, 2015)