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Studies have reported that among SCFAs, butyrate alone is responsible for gut motility, possibly via regulating serotonin, and can be used to increase propulsive gut movement, making it a suitable microbial therapeutic for patients with IBS (Vincent et al., 2018)

Moreover, Hauser et al

doi:10.2105/AJPH.2016.303299

Musar A, McCullagh K, Paul A, et al

Its terminal half-life is approximately 10 to 20 minutes

Among them, butyrate has been considered of significant importance, as it is involved in several functions of physiological importance, such as trans-epithelial transport, amelioration of mucosal inflammation, alleviation of oxidative stress, enforcement of the epithelial barrier, and protection against colorectal cancer (CRC) (Hamer et al., 2008)