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Sample Collection and Preparation All procedures relevant to animals used in this study were carried out in accordance with the UK Animals (Scientific Procedure) Act 1986 and were approved by the University of Hull Ethical Review Process (No

Prolonged use of EGFR/ALK tyrosine kinase inhibitors in non-small cell lung cancer, for instance, can reprogram the local immune milieu, polarizing macrophages toward an immunosuppressive M2 phenotype and upregulating barrier proteins, which collectively impair T cell function [116]

Further reading [edit] Journal of Molecular Biology

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