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doi:10.1017/S0954422419000301

This decline is a major contributor to issues like: Loss of muscle mass Increased body fat Reduced energy and stamina Decreased libido and sexual function Weaker bones Thinning skin and hair Impaired mental clarity and mood The good news

The fat-selective mechanism driven by PON2 activation, AMPK signaling and lipophagy in adipose tissue complements GLP-1 RAs, representing a novel strategy for complete obesity resolution [24]

Nakamura K, Ikeuchi T, Nara K, Rhodes CS, Zhang P, Chiba Y, et al

GLP-1 usually only increases insulin production when blood glucose levels are high [11]

[DOI] [PubMed] [Google Scholar] 205.Zhang R., Zhang D., Yang X., Zhang D., Li Q., Wang C., Yang X., Guo H., Xiong Y