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Our findings do not exclude a positive role for endosomal signaling or -arrestin-1 recruitment in acute responses to physiological GLP-1, but highlight how the kinetic context must be taken into account when exploiting noncanonical pathways during drug development

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Cost and access remain significant barriers for many, as these medications can be expensive and may not always be covered by insurance [3]

its a process

doi: 10.1128/CMR.6.4.382 124 KurtzkeJ

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