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Tamoxifen injection in adult mice to activate the Cre system avoids the effects of EGFR deletion on embryological development that occur with the insulin promoter driving cre, without an ERT, and specifically -cell development and maturation

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Antidiabetic medications influence AGEs and the incretin pathway directly or indirectly

5-Amino-1MQ works to increase the available pool of NAD+, a critical fuel for mitochondrial function