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What the Research Says: Efficacy, Benefits, and Limitations In many clinical trials, GLP-1s produce 15-25% body weight loss over roughly 1 year in people with obesity under good care

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Each health insurance company has different guidelines on weight loss medication coverage, and these benefits vary between the companys various health plans

This is particularly relevant for women over 40 , where perimenopause and declining estrogen are already shifting insulin sensitivity